Born in Athens, Greece in 1966, Frosso Mantziou holds a BA in Archaeology.
After a year as Chief Librarian at the Greek Archaeological Society, she joined the Department of Underwater Antiquities of the Greek Ministry of Culture in 1993, taking part in land and underwater excavations in various parts of Greece.
She later worked for Greenpeace-Greece, as a member of the Fundraising Department in charge of High Donations, and as Administrative Assistant for the Interdisciplinary Institute for Environmental Research.
In 1999 she assumed the post of Press Officer for the Greek Ministry of Culture and in 2000 she was appointed Senior Secretary at the Cabinet of the Greek Deputy Minister for the Environment.
During late 2001-2002 she worked as a public-relations consultant for various environmental organizations (organizing, among other events, the ceremony for the establishment of the MedWet Coordination Unit at Villa Kazouli).
She currently holds the position of Office Manager in MedWet where she begun working in April 2003.
She speaks Greek, English and French.